Severe overweight (obesity) is associated with a reduced quality of life and lower life expectancy. While traditionally severely overweight people are mainly encouraged to change their lifestyle and diet style, more recently, a possible testosterone deficiency has become more of a focus of research in men who are severely overweight. Numerous articles discuss the influence of hormone replacement therapy with testosterone on body weight, body composition and possible sustainable long-term effects.
A very comprehensive overview study summarizes the current status of the available data on testosterone replacement therapy and weight loss:
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